Are you suffering from BPH Symptoms? Urolift® System

Symptoms & Life Impact

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Dealing With Enlarged Prostate

Enlarged prostate, also known as Benign Prostatic Hyperplasia (BPH) is a common condition that can be embarrassing and negatively affects your quality of life.

The goal of the UroLift® System procedure is to relieve symptoms so you can get back to your life and resume your daily activities.

The UroLift® System is the only leading procedure for BPH that does not require heating, cutting, removal, or destruction of prostate tissue. The UroLift® System is a proven option for patients looking for an alternative to medications or major surgery.1

1. Roehrborn, Can J Urol 2017

Manchester Urology Associates, PA Understands

You don’t deserve to be embarrassed or live with a condition that negatively affects your quality of life. Manchester Urology Associates is dedicated to leading the way in urological care in Manchester, NH by putting the patient at the center of our practice. We serve you by utilizing leading technology to best diagnose and treat your conditions.

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About Manchester Urology Associates, PA

Our specialists, Christopher R. Girasole, MD, Cyrus B. Noble, MD, Christian Bartels, MD, Cormac E. O'Neill, MD, and Samuel T. Snipes, MD, see patients in New Hampshire.

Dr. Christopher R. Girasole

He graduated from Yale University and earned his medical degree from Vanderbilt University Medical School.

Dr. Cyrus B. Noble

He graduated from Harvard University and earned his medical degree from Columbia University College of Physicians and Surgeons.

Dr. Christian Bartels

He graduated from Canisius College and earned his medical degree from the University of Pittsburgh School of Medicine.

Dr. Cormac E. O'Neill

He graduated from Boston College and earned his medical degree from the Royal College of Surgeons in Ireland.

Dr. Samuel T. Snipes

He graduated from Arkansas State University and earned his medical degree from the University of Arkansas for Medical Sciences.

Requirements of the UroLift® COE Program

Locations:

Manchester

4 Elliot Way, Suite 200
Manchester, NH 03103

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Dover

10 Members Way, Suite 402
Dover, NH 03820

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Derry

14A Tsienneto Road, Suite 302
Derry, NH 03038

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Portsmouth

330 Borthwick Avenue
Jackson Gray Medical Building - 2nd Floor
Portsmouth, NH 03801

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Manchester Urology at Nashua

17 Riverside Street, Suite 201
Nashua, NH 03062

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Benign Prostatic Hyperplasia, or BPH, is a condition in which the prostate enlarges as men get older. BPH is a very common condition that affects about 42 million men in the US1 and over 660 million aging men worldwide.2,3 Over 40% of men in their 50s and over 70% of men in their 60s have BPH.2 While BPH is a benign condition and unrelated to prostate cancer, it can greatly affect a man’s quality of life.

As the prostate enlarges, it presses on and blocks the urethra, causing bothersome urinary symptoms. If left untreated, BPH can lead to permanent bladder damage.4

Symptoms include: 5,6

Frequent need to urinate both day and night
A sense that you cannot completely empty your bladder
Urgent feeling of needing to urinate

Weak or slow urine stream
Difficulty or delay in starting urination
A urinary stream that stops and starts

Symptoms of BPH can cause loss of productivity, depression, and decreased quality of life.7

If you suffer from the above symptoms, you are not alone. BPH is the leading reason men visit a urologist.8

You can measure your BPH symptoms by taking the International Prostate Symptom Score (IPSS) questionnaire. Sharing this information with your physician will help them understand the severity of your symptoms.

Diagram showing a Normal Prostate compared to Benign Prostatic Enlargement

References:

1. U.S. 2022 estimates based on US Market Model 2022-24 (5-17-22FINAL), which is in part based on data provided by Symphony Health PatientSource® data. This information is provided as is and Symphony Health makes no representations or warranties of any kind, including with respect to accuracy or completeness. PatientSource is a trademark of Symphony Health.

2. Berry, et al., Journal of Urology 1984

3. US Census Bureau international database worldwide population estimates for 2020

4. Tubaro, Drugs Aging 2003

5. Rosenberg, Int J Clin Pract 2007

6. Vuichoud, Can J Urol 2015

7. Speakman, BJUI International 2014

8. IMS Health NDTI Urology Specialty Profile Report 2013

What is the UroLift^® System?

The UroLift® System is a proven minimally invasive procedure to treat an enlarged prostate. It is the only leading enlarged prostate procedure that does not require heating, cutting, removal, or destruction of prostate tissue. The procedure is typically performed as a same-day outpatient procedure, including the office setting, under local anesthesia.1

Advantages of the UroLift^® System

Safe and Effective 2
Risk profile better than those reported for surgical procedures such as TURP 3
Rapid symptom relief 4, better than reported for medications 5
Only leading BPH procedure shown not to cause new and lasting sexual dysfunction *2,5,6
Covered by Medicare, national, and commercial plans, when medical criteria are met
Typically, no catheter is required after treatment 4,6 feeling of needing to urinate

How does The UroLift^® System Work?

Step 1

The UroLift® Delivery Device is placed through the obstructed urethra to access the enlarged prostate.

Step 2

Small UroLift® Implants are permanently placed to lift and hold the enlarged prostate tissue out of the way and increase the opening of the urethra.

Step 3

The UroLift® Delivery Device is removed, leaving an open urethra designed to provide relief.

*No instances of new, sustained erectile or ejaculatory dysfunction in the L.I.F.T pivotal study

Indicated for the treatment of symptoms of an enlarged prostate up to 100 cc in men 45 years or older. As with any medical procedure, individual results may vary. Most common side effects are temporary and include pain or burning with urination, blood in the urine, pelvic pain, urgent need to urinate, and/or the inability to control the urge.4 Rare side effects, including bleeding and infection, may lead to a serious outcome and may require intervention. Speak with your doctor to determine if you may be a candidate.

References:

1. Shore, Can J Urol 2014

2. Roehrborn, Can J Urol 2017

3. Sonksen, EU J Urol, 2015

4. Roehrborn, J Urology 2013

5. AUA BPH Guidelines 2003, 2020

6. McVary, J Sex Med 2016

Hear from patients who chose the UroLift^® System

Read Steve's Story

Steve K. "Mr. Gadget" wanted to stop taking BPH medications.

Read Van's Story

Early on, Van M's active lifestyle was hindered by BPH Symptoms.

Read David's Story

David B. had severe BPH symptoms that put his medical career at risk.

Dwight shares his story.

Ken W. shares his story.

John M. shares his story.

Bladder Disease Progression

Even watchful waiting has its risks. Bladder outlet obstruction could result in irreversible bladder damage if left untreated.1

1. Tubaro, Drug Aging 2003

If you have been diagnosed with an enlarged prostate due to BPH, consult with
your physician to determine which treatment is right for you.

Treatment options may include:

Watchful Waiting: For men with mild symptoms, this may be a viable option until their condition shows signs of worsening.1 However, it is important to note that, in a study, 87% of men who elected watchful waiting experienced a worsening of symptoms over a 4-year time period.2

Medications: Your doctor may prescribe BPH medication, just one or even a combination of BPH medications that may help alleviate your urinary symptoms. These medications are effective and may improve your BPH symptoms; however, some men may not experience enough relief. In addition, some men experience bothersome side effects from BPH medication. Either or both of these things may lead them to discontinue the medication.3-6

Minimally Invasive Treatments: These are procedures which can often be done as an outpatient procedure with milder forms of anesthesia than what is used in a hospital operating room. They typically have fewer complications than traditional surgery.7

The UroLift^® System uses small implants to open the prostate blockage and does not require heating or cutting tissue. The procedure is typically performed under local anesthesia in a doctor’s office and patients typically return home the same day without a catheter.6,8 The UroLift® System offers rapid symptom relief with a low-risk profile.6 As the procedure does not destroy tissue, recovery on average is more rapid than for TURP patients. It is the only leading BPH procedure shown to provide symptom relief while also preserving sexual function.*8-11 Patients may experience short·term pelvic pain and light blood in the urine.6,7

Another minimally-invasive BPH treatment is RezumTM Water Vapor Therapy. This is a form of thermal therapy in which the prostate is heated with steam. Another form of thermal therapy called Transurethral Microwave Therapy (TUMT) uses microwaves to destroy tissue.7 They can typically be done at a doctor’s office with local anesthesia and patients can usually go home the same day as the procedure. These procedures generally have fewer complications than traditional surgery. A catheter is typically required for a few days after the procedure and recovery may take a few weeks.11-13

Traditional Surgery: Common traditional BPH surgeries include transurethral resection of the prostate
(TURP) and laser photoselective vaporization of the prostate (GreenlightTM laser PVP). These procedures are the most aggressive treatment option and can be effective. Recovery can take time and is accompanied by a higher risk of complications.1 Less commonly performed surgeries include Aquablation® therapy and Holmium Laser Enucleation of the Prostate (HoLEP).7 Aquablation® therapy uses a high-pressure water jet to remove prostate tissue, whereas HoLEP uses a laser to remove the prostate tissue. Traditional surgery can offer significant relief of symptoms and help you improve your quality of life.7

Rezum and GreenLight are trademarks of Boston Scientific. Aquablation is a trademark of PROCEPT BioRobotics Corp.

References:

*No instances of new, sustained erectile or ejaculatory dysfunction in the L.I.F.T. pivotal study

1. AUA BPH Guidelines 2003. Updated 2010.

2. Djavan, Urology 2004

3. Chang DF, Campbell JR, J Cataract Refract Surg. 2005

4. Duan et al, Pharmacoepidemiol Drug Saf. 2018

5. Welk et al, JAMA Intern Med. 2017

6. Roehrborn, J Urol 2013

7. Roehrborn, Can J Urol 2017

8. Shore Can J Urol 2014

9. Tutrone, Can J Urol 2020

10. Eure, et al., AUA 2020

11. Sonksen, et al., Eur Urol 2015

12. McVary, J Urol 2016

13. McVary, J Urol 2020; AUA abstract LBA01-06 5-year Rezum

Are you suffering from BPH Symptoms?

Symptoms & Life Impact

Dealing With Enlarged Prostate

Manchester Urology Associates, PA Understands